The Journal of Orthopedics Research and Rehabilitation welcomes scholarly papers inorthopaedic surgery, physical therapy and rehabilitation, neurosurgery, neurology and clinic anesthesiology and reanimation. This journal is indexed by indices that are considered international scientific journal indices (DRJI, ESJI, OAJI, etc.). According to the current Associate Professorship criteria, it is within the scope of International Article 1-d. Each article published in this journal corresponds to 5 points.

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Exercise in head and neck cancer: review of the last 5 years
Head and Neck Cancers (HNC) is a significant global health issue with increasing incidence and mortality rates. Physiotherapy in head and neck cancer is crucial for managing post-treatment challenges, reducing functional limitations, improving quality of life, and achieving maximum physical independence. This review examined full-text articles published between 2019 and 2024 on PubMed using keywords related to head and neck neoplasms, exercise, and rehabilitation. Out of sixteen accessed articles, eleven met the inclusion criteria. The reviewed studies primarily focused on supervised aerobic and resistance exercises post-surgery. Aerobic exercise training showed no reduction in heart rate and aerobic endurance parameters pre- and post-treatment among participants, while the control group exhibited significant decreases, emphasizing the necessity of aerobic exercise during chemotherapy. Muscle strength exercises reported significant increases in overall muscle strength and positive changes in fatigue levels and quality of life in the exercise groups. Stretching exercises were performed in studies, replacing warm-up and cool-down periods. Qi-gong exercises administered to HNC patients resulted in significant improvements in quality of life, sleep quality, and cancer-related fatigue. The limited number of exercise studies in HNC highlights the need for more research. The reviewed studies demonstrate the importance of incorporating supervised exercise in the rehabilitation of HNC patients, particularly to mitigate the side effects of chemotherapy. Future research should explore home exercise programs and telerehabilitation to accommodate patients unable to participate in supervised exercise programs. Exercise plays a critical role in the rehabilitation of HNC patients, improving physical function, reducing fatigue, and enhancing quality of life, thus emphasizing the need to incorporate structured exercise programs into HNC treatment plans to optimize patient outcomes.

1. Sung H, Ferlay J, Siegel RL, et al. Global cancer statistics 2020:GLOBOCAN estimates of incidence and mortality worldwide for 36cancers in 185 countries. CA Cancer J Clin. 2021;71(3):209-249.
2. Smith CDL, McMahon AD, Lyall DM, et al. Development and externalvalidation of a head and neck cancer risk prediction model. Head Neck.2024. doi:10.1002/hed.27834
3. Mendenhall WM, Hinerman RW, Amdur RJ, et al. Postoperativeradiotherapy for squamous cell carcinoma of the head and neck. ClinMed Res. 2006;4(3):200-208.
4. Tsimberidou AM. Targeted therapy in cancer. Cancer Chemo Pharma.2015;76:1113-1132.
5. Schuster M, Nechansky A, Kircheis R. Cancer immunotherapy. BiotechJ Healthcare Nutri Techno. 2006;1(2):138-147.
6. Agostinis P, Berg K, Cengel KA, et al. Photodynamic therapy of cancer:an update. CA Cancer J Clin. 2011;61(4):250-281.
7. Schutte HW, Heutink F, Wellenstein DJ, et al. Impact of time todiagnosis and treatment in head and neck cancer: a systematic review.Otolaryngo-head Neck Surg. 2020;162(4):446-457.
8. Mody MD, Rocco JW, Yom SS, Haddad RI, Saba NF. Head and neckcancer. The Lancet. 2021;398(10318):2289-2299.
9. Schorn L, Lommen J, Sproll C, et al. Evaluation of patient specificcare needs during treatment for head and neck cancer. Oral Oncology.2020;110:104898.
10. Felser S, Behrens M, Liese J, et al. Feasibility and effects of a supervisedexercise program suitable for independent training at home on physicalfunction and quality of life in head and neck cancer patients: a pilotstudy. Integrat Cancer Therap. 2020;19:1534735420918935.
11. van Vulpen JK, Witlox L, Methorst-de Haan AC, et al. Perceivedfacilitators and barriers by esophageal cancer survivors participating ina post-treatment exercise program. Support Care Cancer. 2023;31(6):320.
12. Anandavadivelan P, Malberg K, Vikstrom K, et al. Home-basedphysical activity after treatment for esophageal cancer-A randomizedcontrolled trial. Cancer Med. 2023;12(3):3477-3487.
13. Wen L, Chen X, Cui Y, Zhang M, Bai X. Effects of Baduanjin exercisein nasopharyngeal carcinoma patients after chemoradiotherapy: arandomized controlled trial. Support Care Cancer. 2023;31(1):79.
14. Allen SK, Brown V, White D, et al. Multimodal prehabilitation duringneoadjuvant therapy prior to esophagogastric cancer resection: effecton cardiopulmonary exercise test performance, muscle mass andquality of life-a pilot randomized clinical trial. Annals Surg Oncology.2022:1-12.
15. Lin K-Y, Cheng H-C, Yen C-J, et al. Effects of exercise in patientsundergoing chemotherapy for head and neck cancer: a pilot randomizedcontrolled trial. Inter J Environment Res Public Health. 2021;18(3):1291.
16. Hu Q, Zhao D. Effects of resistance exercise on complications, cancer-related fatigue and quality of life in nasopharyngeal carcinoma patientsundergoing chemoradiotherapy: a randomised controlled trial.European J Cancer Care. 2021;30(1):e13355.
17. Thomas A, D’Silva C, Mohandas L, Pais SM, Samuel SR. Effect of muscleenergy techniques V/S active range of motion exercises on shoulderfunction post modified radical neck dissection in patients with headand neck cancer-a randomized clinical trial. APJCP. 2020;21(8):2389.
18. Simonsen C, Thorsen-Streit S, Sundberg A, et al. Effects of high-intensity exercise training on physical fitness, quality of life andtreatment outcomes after oesophagectomy for cancer of the gastro-oesophageal junction: preset pilot study. BJS Open. 2020;4(5):855-864.
19. Lavigne C, Twomey R, Lau H, Francis G, Culos-Reed SN, Millet GY.Feasibility of eccentric overloading and neuromuscular electricalstimulation to improve muscle strength and muscle mass after treatmentfor head and neck cancer. J Cancer Survivorship. 2020;14:790-805.
20. YenCJ, Hung CH, Kao CL, et al. Multimodal exercise ameliorates exerciseresponses and body composition in head and neck cancer patientsreceiving chemotherapy. Support Care Cancer. 2019;27(12):4687-4695.doi:10.1007/s00520-019-04786-1
21. Samuel SR, Maiya AG, Fernandes DJ, et al. Effectiveness of exercise-based rehabilitation on functional capacity and quality of life in headand neck cancer patients receiving chemo-radiotherapy. Support CareCancer. 2019;27(10):3913-3920. doi:10.1007/s00520-019-04750-z
Volume 2, Issue 3, 2024
Page : 59-62